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TH17 Cells in Health and Disease
Editor: Shuiping Jiang
Publisher: Springer
New York
Hardcover, 536 p. 38 illus. 29 in color
ISBN: 978-1-4419-9370-0
Book website: http://www.springer.com/biomed/immunology/book/978-1-4419-9370-0
Table
of Contents:
Part One: The Immunology of IL-17 Family and TH17 Cells
Chapter 1 From Th1/Th2 paradigm to
Th17 cells: Le roi est mort, vive le roi
Amit Awasthi and Vijay K Kuchroo, Harvard University, USA
Chapter 2 Th17 cytokines: characteristics, regulation,
and biological function
Pornpimon Angkasekwinai and Chen Dong, University of Texas and MD Anderson Cancer Center, USA
Chapter 3 TGF-beta
and Th17 cells
Samuel Huber, Enric Esplugues, Richard Flavell, Yale University, USA
Chapter 4 IL-6: a pleiotropic cytokine and Th17 cells
Akihiro
Kimura, Tetsuji Naka and Tadamitsu Kishimoto, Osaka University, Japan
Chapter 5 Apoptosis and Th17 cell differentiation
J. Magarian Blander, Mount Sinai School
of Medicine, USA
Chapter 6 IL-1 and innate immunity in the differentiation of Th17 cells
Stephen J. Lalor, Caroline E. Sutton and Kingston
H.G. Mills, Trinity College, Ireland
Chapter 7 Negative regulation of Th17 differentiation
Mark S. Sundrud and Sergei Koralov, Harvard
University, USA
Chapter 8 Signal transduction in Th17 cell differentiation
Xiang-Ping Yang, John J. O’Shea, Kamran Ghoreschi and
Arian Laurence, National Institutes of Health, USA
Chapter 9 Structure and IL-17 receptor signaling
Michael Tsang and Sarah L. Gaffen, University
of Pittsburgh, USA
Chapter 10 Trafficking receptors and migration of Th17 cell subsets
Chang H. Kim, Purdue University, USA
Chapter 11 Plastic
T cells: Recycling effector functions?
Eleftherios I. Agorogiannis, Stephen P. Cobbold and Herman Waldmann, University of Oxford, UK
Part Two: TH17 Cells
in Health and Disease
Chapter 12 Human Th17 cells
Francesco Annunziato, Lorenzo Cosmi, Francesco Liotta, Enrico
Maggi and Sergio Romagnani, University of Florence, Italy
Chapter 13 Th17 cytokines in primary mucosal immunity
Jay K. Kolls and Shabaana A. Khader, Louisiana
State University, USA
Chapter 14 Th17 cells and IL-23 in gut inflammation
Giovanni Monteleone, Massimiliano Sarra,
Francesco Pallone, Thomas T MacDonald, University Tor Vergata of Rome, Italy
Chapter 15 The roles of IL-17A and IL-17F in mucosal
infection and allergy
Harumichi Ishigame, Susumu Nakae, and Yoichiro Iwakura, University of Tokyo, Japan
Chapter 16 Th17
cells in fungal infections
Teresa Zelante, Antonella De Luca and Luigina Romani, University of Perugia, Italy
Chapter 17 IL-17
cells in organ transplantation rejection and tolerance
Julia Tsang, Ling Lu and Shuiping Jiang, Imperial College London, UK
Chapter 18 Th17 cells, proteins associated
with Th17 polarization, and their role in graft-versus-host disease
Jonathan S Serody, Timothy P Moran, Bruce R Blazar, University
of Minnesota, USA
Chapter 19 Interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease:
A tale of Yin and Yang
Xuebin Liu, Stewart Leung, Lei Fang, Xi Chen, Taylor Guo and Jingwu Zhang, GSK R&D China, China
Chapter 20 The role
of interleukin-17 in systemic lupus erythematosus
José C. Crispín, Vasileios C. Kyttaris, George C. Tsokos, Harvard University, USA
Chapter 21 IL-17
in B cell biology and systemic lupus erythematosus
Agnès Doreau-Bastid, Jeremy Bastid, Alexandre Belot, Jean-François Eliaou and Nathalie
Bonnefoy-Berard, INSERM, France
Chapter 22 IL-17 and Th17 cells in human rheumatoid arthritis
Pierre Miossec, University of Lyon, France
Chapter 23 The role
of the IL-23 / Th17 immune pathway in the pathogenesis of arthritis
Erik Lubberts, University of Rotterdam, the Netherlands
Chapter 24 The roles
of IL-22 and its related family members in the pathogenesis of psoriasis
Patricia Valdez and Wenjun Ouyang, Genentech,
USA
Chapter 25 IL-23/Th17 pathway in psoriasis and inflammatory skin diseases
Kristine E. Nograles, Batya Davidovici and
James G. Krueger, Rockefeller University, USA
Chapter 26 Th17 cells in the tumor microenvironment
Cailin Moira Wilke and Weiping Zou, University
of Michigan, USA
Chapter 27 IL-17-producing NKT cells in airway inflammation
Dale T Umetsu, and Rosemarie H. DeKruyff, Harvard University,
USA
Chapter 28 IL-17-producing gd T cells in autoimmune disease
Rebecca L. O’Brien, Philip L. Simonian, Yafei Huang, Christina L. Roark, Niyun Jin, M. Kemal
Aydintug, Jennifer L. Chain, Andrew P. Fontenot, and Willi K. Born, National Jewish Health, USA
About
this Book
“About 25 years ago, Mosmann & Coffman
introduced the TH1 / TH2 paradigm of T helper cell differentiation, which helped explain many aspects of adaptive immunity
from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation.
However, TH1 / TH2 paradigm could not adequately explain development
of certain inflammatory responses which provided impetus for the discovery of a new subset of T cells called TH17 cells. After
the discovery of differentiation and transcription factors for TH17 cells, it was clear that TH17 cells represent an independent
subset of T cells with specific functions in eliminating certain extracellular pathogens, presumably not adequately handled
by TH1 or TH2 cells. The major role of TH17 cells has been described in inducing autoimmune tissue inflammation.
The discovery of TH17 cells has expanded the TH1 / TH2 paradigm,
and the integration of TH17 cells with TH1 and TH2 effector T cells is beginning to explain the underlying mechanisms of tissue
inflammation in a number of infections and autoimmune disease settings.”
- From Chapter One by Vijay K. Kuchroo, Harvard University, USA
“The recent identified Interleukin 17 (IL-17) cytokine family contributes to immunity to infectious diseases
and chronic inflammatory diseases. Further studies on the regulation and function of this important cytokine family may provide
better understanding on the roles of the IL-17 family in immune-mediated diseases; such knowledge may lead to the development
of immunotherapeutic strategies for treatment of several inflammatory diseases.”
- From Chapter Two by Chen Dong, University of Texas and MD Anderson Cancer Center, USA
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